About us

Our research focuses on understanding 1) the molecular mechanisms involved in the development of neuronal circuitry, and 2) the disease mechanisms responsible for changes in or loss of neuronal connectivity during motor neuron disease (ALS) and other neurodegenerative diseases. RNA biology (e.g. non-coding RNAs), (single cell) omics, mouse genetics, humanized cell models (iPSC, organoids, microfluidics), molecular cell biology, and (light sheet) microscopy play a central role in many of our projects.