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Siebold C, Yamashita T, Monnier PP, Mueller BK, Pasterkamp RJ (2016). RGMs: Structural insights, molecular regulation and downstream signaling. Trends in Cell Biology, in press.
Engelen-Lee Y, Blokhuis AM, Spliet WGM, Pasterkamp RJ, Aronica E, Demmers JAA, Broekhuizen R, Nardo G, Bovenschen N, Van den Berg LH (2016). Proteomic profiling of the spinal cord in ALS: decreased ATP5D levels suggest synaptic dysfunction in ALS pathogenesis. ALS Frontotemp Degeneration, in press.
Zuko A, Aguro-Ando A, Post H, Taggenbrock RLRE, Van Dijk RE, Altelaar M, Heck AJR, Petrenko AG, Van der Zwaag B, Shimoda Y, Pasterkamp RJ, Burbach JPH (2016) Association of cell adhesion molecules contactin-6 and latrophilin-1 regulates neuronal apoptosis. Front Mol Neuroscience, in press.
Reschke CR, LFA Silva , Norwood BA, Senthilkumar K, Morris G, Sanz-Rodriguez A, Conroy RM, Costard L, Neubert V, Bauer S, Farrell MA, O’Brien DF, Delanty N, Schorge S, Pasterkamp RJ, Rosenow F, Henshall DC (2016). Potent anti-seizure effects of locked nucleic acid antagomirs targeting miR-134 in multiple mouse and rat models of epilepsy. Mol Therapy – Nucl Acids, in press.
Pronker MF, Lemstra S, Snijder J, Heck AJR, Thies-Weesie DME, Pasterkamp RJ, Janssen BJC (2016). Structural basis of myelin-associated glycoprotein adhesion and signalling. Nature Communications, in press.
Henshall DC, Hamer HM, Pasterkamp RJ, Goldstein DB, Kjems J, Prehn JH, Schorge S, Lamottke K, Rosenow F (2016). MicroRNAs in epilepsy: pathophysiology and clinical utility. Lancet Neurology 15, 1368-1376.
Schellino R, Trova S, Cimino I, Farinetti A, Jongbloets BC, Pasterkamp RJ, Panzica G, Giacobini P, De Marchis S, Peretto P (2016). Opposite-sex attraction in male mice requires testosterone-dependent regulation of adult olfactory bulb neurogenesis. Sci Rep 6, 36063.
van Rossum D, Verheijen BM, Pasterkamp RJ (2016). Circular RNAs: Novel Regulators of Neuronal Development. Front Mol Neurosci 9, 74.
van Rheenen W, Shatunov A, Dekker AM, McLaughlin RL, Diekstra FP, Pulit SL, van der Spek RA, Võsa U, de Jong S, Robinson MR, Yang J, Fogh I, van Doormaal PT, Tazelaar GH, Koppers M, Blokhuis AM, Sproviero W, Jones AR, Kenna KP, van Eijk KR, Harschnitz O, Schellevis RD, Brands WJ, Medic J, Menelaou A, Vajda A, Ticozzi N, Lin K, Rogelj B, Vrabec K, Ravnik-Glavač M, Koritnik B, Zidar J, Leonardis L, Grošelj LD, Millecamps S, Salachas F, Meininger V, de Carvalho M, Pinto S, Mora JS, Rojas-García R, Polak M, Chandran S, Colville S, Swingler R, Morrison KE, Shaw PJ, Hardy J, Orrell RW, Pittman A, Sidle K, Fratta P, Malaspina A, Topp S, Petri S, Abdulla S, Drepper C, Sendtner M, Meyer T, Ophoff RA, Staats KA, Wiedau-Pazos M, Lomen-Hoerth C, Van Deerlin VM, Trojanowski JQ, Elman L, McCluskey L, Basak AN, Tunca C, Hamzeiy H, Parman Y, Meitinger T, Lichtner P, Radivojkov-Blagojevic M, Andres CR, Maurel C, Bensimon G, Landwehrmeyer B, Brice A, Payan CA, Saker-Delye S, Dürr A, Wood NW, Tittmann L, Lieb W, Franke A, Rietschel M, Cichon S, Nöthen MM, Amouyel P, Tzourio C, Dartigues JF, Uitterlinden AG, Rivadeneira F, Estrada K, Hofman A, Curtis C, Blauw HM, van der Kooi AJ, de Visser M, Goris A, Weber M, Shaw CE, Smith BN, Pansarasa O, Cereda C, Del Bo R, Comi GP, D’Alfonso S, Bertolin C, Sorarù G, Mazzini L, Pensato V, Gellera C, Tiloca C, Ratti A, Calvo A, Moglia C, Brunetti M, Arcuti S, Capozzo R, Zecca C, Lunetta C, Penco S, Riva N, Padovani A, Filosto M, Muller B, Stuit RJ; PARALS Registry.; SLALOM Group.; SLAP Registry.; FALS Sequencing Consortium.; SLAGEN Consortium.; NNIPPS Study Group., Blair I, Zhang K, McCann EP, Fifita JA, Nicholson GA, Rowe DB, Pamphlett R, Kiernan MC, Grosskreutz J, Witte OW, Ringer T, Prell T, Stubendorff B, Kurth I, Hübner CA, Leigh PN, Casale F, Chio A, Beghi E, Pupillo E, Tortelli R, Logroscino G, Powell J, Ludolph AC, Weishaupt JH, Robberecht W, Van Damme P, Franke L, Pers TH, Brown RH, Glass JD, Landers JE, Hardiman O, Andersen PM, Corcia P, Vourc’h P, Silani V, Wray NR, Visscher PM, de Bakker PI, van Es MA, Pasterkamp RJ, Lewis CM, Breen G, Al-Chalabi A, van den Berg LH, Veldink JH (2016). Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis. Nat Genet 48, 1043-8.
Kong Y, Janssen BJ, Malinauskas T, Vangoor VR, Coles CH, Kaufmann R, Ni T, Gilbert RJ, Padilla-Parra S, Pasterkamp RJ*, Jones EY* (2016). Structural Basis for Plexin Activation and Regulation. Neuron 91, 548-60. *Shared senior authors. Preview in Neuron.
Sudria-Lopez E, Koppers M, de Wit M, van der Meer C, Westeneng HJ, Zundel CA, Youssef SA, Harkema L, de Bruin A, Veldink JH, van den Berg LH, Pasterkamp RJ (2016). Full ablation of C9orf72 in mice causes immune system-related pathology and neoplastic events but no motor neuron defects. Acta Neuropathol 132, 145-7.
Blokhuis AM, Koppers M, Groen EJ, van den Heuvel DM, Dini Modigliani S, Anink JJ, Fumoto K, van Diggelen F, Snelting A, Sodaar P, Verheijen BM, Demmers JA, Veldink JH, Aronica E, Bozzoni I, den Hertog J, van den Berg LH, Pasterkamp RJ (2016). Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways. Acta Neuropathol 132, 175-96.
Harschnitz O, van den Berg LH, Johansen LE, Jansen MD, Kling S, Vieira de Sá R, Vlam L, van Rheenen W, Karst H, Wierenga CJ, Pasterkamp RJ*, van der Pol WL* (2016). Autoantibody pathogenicity in a multifocal motor neuropathy induced pluripotent stem cell-derived model. Ann Neurol 80, 71-88. *Shared senior authors.
van Es MA, Kruitwagen-van Reenen ET, Schröder CD, Pasterkamp RJ, Veldink JH, van den Berg LH (2016). Amyotrophic lateral sclerosis, a heterogeneous disorder. Ned Tijdschr Geneeskd 160, A9658.
Van Rijn A, Paulis L, Te Riet J, Vasaturo A, Reinieren-Beeren I, van der Schaaf A, Kuipers AJ, Schulte LP, Jongbloets BC, Pasterkamp RJ, Figdor CG, van Spriel AB, Buschow SI (2015). Semaphorin 7A Promotes Chemokine-Driven Dendritic Cell Migration. J Immunol 196, 459-468.
Dekker AM, Seelen M, van Doormaal PT, van Rheenen W, Bothof RJ, van Riessen T, Brands WJ, van der Kooi AJ, de Visser M, Voermans NC, Pasterkamp RJ, Veldink JH, van den Berg LH, van Es MA (2015) Large-scale screening in sporadic amyotrophic lateral sclerosis identifies genetic modifiers in C9orf72 repeat carriers. Neurobiol Aging 39, 220.e9-15.
Van Erp S, van den Heuvel DMA, Fujita Y, Robinson R, Hellemons AJCGM, Adolfs Y, Van Battum EY, Blokhuis AM, Kuijpers M, Demmers J, Hedman H, Hoogenraad CC, Siebold C, Yamashita T, Pasterkamp RJ (2015) Lrig2 negatively regulates ectodomain shedding of axon guidance receptors by ADAM proteases. Dev Cell 35, 537-552. F1000
Van Beuningen SFB, Will L, Harterink M, Chazeau A, van Battum EY, Frias CP, Franker MAM, Katrukha EA, Stucchi R, Vocking K, Antunes AT, Slenders L, Doulkeridou S, Sillevis Smitt P, Altelaar MAF, Post JA, Akhmanova A, Pasterkamp RJ, Kapitein LC, de Graaff E, Hoogenraad CC (2015) TRIM46 controls neuronal polarity and axon specification by driving the formation of parallel microtubule arrays. Neuron 88, 1208-1226.
Morello F, Prasad AA, Rehberg K, Vieira de Sá R, Antón-Bolaños N, Leyva-Diaz E, Adolfs Y, Tissir F, López-Bendito G, Pasterkamp RJ (2015) Frizzled3 Controls Axonal Polarity and Intermediate Target Entry during Striatal Pathway Development. J Neurosci 35, 14205-19.
Koppers M, Blokhuis AM, Westeneng HJ, Terpstra ML, Zundel CA, Vieira de Sá R, Schellevis RD, Waite AJ, Blake DJ, Veldink JH, Van den Berg LH, Pasterkamp RJ (2015) C9orf72 ablation in mice does not cause motor neuron degeneration or motor deficits. Annals of Neurology 78, 426-438.
Parkash J, Messina A, Langlet F, Cimino I, Loyens A, Mazur D, Gallet S, Balland E, Malone SA, Pralong F, Cagnoni G, Schellino R, De Marchis S, Mazzone M, Pasterkamp RJ, Tamagnone L, Prevot V, Giacobini P (2015) Semaphorin7A regulates neuroglial plasticity in the adult hypothalamic median eminence. Nature Communications 6, 6385.
Van Battum EY, Brignani S, Pasterkamp RJ (2014). Axon guidance proteins in neurological disease. Lancet Neurology 14, 532-546.
Hessel EV, de Wit M, Wolterink-Donselaar IG, Karst H, de Graaff E, van Lith HA, de Bruijn E, de Sonnaville S, Verbeek NE, Lindhout D, de Kovel CG, Koeleman BP, van Kempen M, Brilstra E, Cuppen E, Loos M, Spijker SS, Kan AA, Baars SE, van Rijen PC, Gosselaar PH, Groot Koerkamp MJ, Holstege FC, van Duijn C, Vergeer J, Moll HA, Taubøll E, Heuser K, Ramakers GM, Pasterkamp RJ, van Nieuwenhuizen O, Hoogenraad CC, Kas MJ, de Graan PN (2015) Identification of Srp9 as a febrile seizure susceptibility gene. Ann Clin Transl Neurol 1, 239-50.
Schmidt ER, Brignani S, Adolfs Y, Lemstra S, Demmers J, Vidaki M, Donahoo AL, Lilleväli K, Vasar E, Richards LJ, Karagogeos D, Kolk SM, Pasterkamp RJ (2014). Subdomain-mediated axon-axon signaling and chemoattraction cooperate to regulate afferent innervation of the lateral habenula. Neuron 83, 372-387.
Van Battum EY, Gunput RA, Lemstra S, Groen EJ, Yu KL, Adolfs Y, Zhou Y, Hoogenraad CC, Yoshida Y, Schachner M, Akhmanova A, Pasterkamp RJ (2014). The intracellular redox protein MICAL-1 regulates the development of hippocampal mossy fibre connections. Nature Communications 5, 4317.
Yau KW, Van Beuningen SFB, Cunha-Ferreira I, Cloin BMC, Tas RP, Katrukha EA, Van Battum EY, Schatzle P, Jiang K, Will L, Mikhaylova M, Wulf PS, Harterink M, Pasterkamp RJ, Akhmanova A, Kapitein LC, Hoogenraad CC (2014) Microtubule minus-end binding protein CAMPSAP2 controls axon specification and denrite development. Neuron 82, 1058-1073.
Jaarsma D, Van den Berg R, Wulf PS, Van Erp S, Keijzer N, Schlager MA, De Graaff E, De Zeeuw CI, Pasterkamp RJ, Akhmanova A, Hoogenraad CC (2014). Essential non-cell-autonomous function for Bicaudal-D2 (BICD2) in radial cerebellar granule cell migration. Nature Communications 5, 3411.
Jongbloets BC, Pasterkamp RJ (2014). Semaphorin signaling during development. Development 141, 3292-7.
Diekstra FP, Van Deerlin VM, van Swieten JC, Al-Chalabi A, Ludolph AC, Weishaupt JH, Hardiman O, Landers JE, Brown RH Jr, van Es MA, Pasterkamp RJ, Koppers M, Andersen PM, Estrada K, Rivadeneira F, Hofman A, Uitterlinden AG, van Damme P, Melki J, Meininger V, Shatunov A, Shaw CE, Leigh PN, Shaw PJ, Morrison KE, Fogh I, Chiò A, Traynor BJ, Czell D, Weber M, Heutink P, de Bakker PI, Silani V, Robberecht W, van den Berg LH, Veldink JH. (2014). C9orf72 and UNC13A are shared risk loci for amyotrophic sclerosis and frontotemporal dementia: A genome-wide meta-analysis. Ann Neurol 76, 120-33.
Van Gestel MA, Van Erp S, Sanders LE, Brans MA, Luijendijk MC, Merkestein M, Pasterkamp RJ, Adan RA (2014). shRNA-induced saturation of the microRNA pathway in the rat brain. Gene Therapy 21, 205-211.
Van den Heuvel DM, Harschnitz O, Van den Berg LH, Pasterkamp RJ (2014). Taking a risk: a therapeutic focus on ataxin-2 in amyotrophic lateral sclerosis? Trends Mol Medicine 20, 25-35.
Manitt C, Eng C, Pokinko M, Ryan RT, Torres-Berrio A, Lopez, JP, Yogendran SV, Daubaras MJ, Grant A, Schmidt ER, Tronche F, Krimpenfort P, Cooper HM, Pasterkamp RJ, Kolb B, Turecki G, Wong TP, Nestler EJ, Giros B, Flores C (2013). DCC orchestrates the development of the prefrontal cortex during adolescence and is altered in psychiatric patients. Transl Psychiatry e338.
Groen EJ, Fumoto K, Blokhuis AM, Engelen-Lee J, Zhou Y, Van den Heuvel DM, Koppers M, Van Diggelen F, Van Heest J, Demmers JA, Kirby J, Shaw PJ, Aronica E, Spliet WG, Veldink JH, Van den Berg LH, Pasterkamp RJ (2013). ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN. Hum Mol Genetics 22, 3690-3704.
Bell CH, Healey E, Van Erp S, Bishop B, Tang C, Gilbert RJC, Aricescu AR, Pasterkamp RJ, Siebold C (2013). Structure of the repulsive guidance molecule (RGM)-Neogenin signaling hub. Science 341, 77-80.
Auger ML, Manitt C, Pasterkamp RJ, Flores C (2013). Unc5c haploinsufficienct phenotype: striking similarities with the dcc haploinsufficiency model. Eur J Neurosci 38, 2853-2863.
van der Vaart B, van Riel WE, Doodhi H, Kevenaar JT, Katrukha EA, Gumy L, Bouchet BP, Grigoriev I, Spangler SA, Yu KL, Wulf PS, Wu J, Lansbergen G, van Battum EY, Pasterkamp RJ, Mimori-Kiyosue Y, Demmers J, Olieric N, Maly IV, Hoogenraad CC, Akhmanova A (2013). CFEOM1-associated kinesin KIF21A is a cortical microtubule growth inhibitor. Developmental Cell 27, 145-160. F1000
Blokhuis AM, Groen EJ, Koppers M, Van den Berg LH, Pasterkamp RJ (2013). Protein aggregation in ALS. Acta Neuropathologica 125, 777-794.
Manitt C, Eng C, Pokinko M, Ryan RT, Torres-Berrío A, Lopez JP, Yogendran SV, Daubaras MJ, Grant A, Schmidt ER, Tronche F, Krimpenfort P, Cooper HM, Pasterkamp RJ, Kolb B, Turecki G, Wong TP, Nestler EJ, Giros B, Flores C (2013). DCC orchestrates the development of the prefrontal cortex during adolescence and is altered in psychiatric patients. Transl Psychiatry 3, e338.
Van den Heuvel DM, Hellemons AJ, Pasterkamp RJ (2013). Spatiotemporal expression of repulsive axon guidance molecules (RGMs) and their receptor Neogenin in the mouse brain. PloS One 8, e55828.
Blakely BD, Bye CR, Fernando CV, Prasad AA, Pasterkamp RJ, Macheda ML, Stacker SA, Parish C (2013). Ryk, a receptor regulating Wnt5a-mediated neurogenesis and axon morphogenesis of ventral midbrain dopaminergic neurons. Stem Cells Dev 22, 2132-2144.
Kolodkin AL, Pasterkamp RJ (2013). SnapShot: Axon guidance II. Cell 153, 722.
van Spronsen M, van Battum EY, Kuijpers M, Vangoor VR, Rietman ML, Pothof J, Gumy LF, van Ijcken WF, Akhmanova A, Pasterkamp RJ, Hoogenraad CC (2013). Developmental and activity-dependent miRNA expression profiling in primary hippocampal neuron cultures. PloS One 8, e74907.
Pasterkamp RJ, Kolodkin AL (2013). SnapShot: Axon guidance I. Cell 153, 494.
Nott A, Nitarska J, Veenvliet JV, Schacke S, Derijck AA, Sirko P, Muchardt C, Pasterkamp RJ, Smidt MP, Riccio A (2013). S-nitrosylation of HDAC2 regulates the expression of the chromatin-remodelling factor Brm during radial neuron migration. PNAS 110:3113-318.
Jongbloets BC, Ramakers GM, Pasterkamp RJ (2013). Semaphorin7A and its receptors: pleiotropic regulators of immune cell function, bone homeostasis, and neural development. Semin Cell Dev Biol 24, 129-138.
Koppers M, Groen EJN, Van Vught PWJ, Van Rheenen W, Witteveen E, Van Es MA, Pasterkamp RJ, Van den Berg LH, Veldink JH (2013). Screening for rare variants in the coding region of ALS associated genes at 9p21.2 and 19p13.3. Neurobiology of Aging 34, 1518.e5-7.
Trezza V, Damsteegt R, Manduca A, Van Kerkhof LWM, Pasterkamp RJ, Zhou Y, Campolongo P, Cuomo V, DiMarzo V, Vanderschuren LJ (2012). Endocannabinoids in amygdala and nucleus accumbens mediate social play reward in adolescent rats. J Neurosci 32, 14899-14908.
Pasterkamp RJ (2012). Getting neural circuits into shape with Semaphorins. Nature Reviews Neuroscience 13, 605-618.
Chakrabarty K, Von Oerthel L, Hellemons JCGM, Clotman F, Groot Koerkamp M, Holstege F, Pasterkamp RJ*, Smidt MP* (2012). Genome wide expression profiling of the mesodiencephalic region identifies novel factors involved in early and late dopaminergic development. Biology Open 1, 693-704. * Shared senior authors.
Kan AA, van Erp S, Derijck AHAA, de Wit M, Hessel EVS, O’Duibhir E, Van Rijen PC, Gosselaar PH, de Graan PNE, Pasterkamp RJ (2012). Genome-wide microRNA profiling of human temporal lobe epilepsy reveals modulators of the immune response. Cell Mol Life Sciences 69, 3127-3145.
Schmidt ER, Morello F, Pasterkamp RJ (2012). Dissection and culture of mouse dopaminergic and striatal explants in three-dimensional collagen matrix assays. J Vis Exp pii 3691.
Blauw HM, van Rheenen W, Koppers M, Van Damme P, Waibel S, Lemmens R, van Vught PW, Meyer T, Schulte C, Gasser T, Cuppen E, Pasterkamp RJ, Robberecht W, Ludolph AC, Veldink JH, van den Berg LH (2012). NIPA1 polyalanine repeat expansions are associated with amyotrophic lateral sclerosis. Human Molecular Genetics 21, 2497-2502.
Groen EJN, Van Rheenen W, Koppers M, Van Doormaal PTC, Vlam L, Diekstra FP, Doojies D, Pasterkamp RJ, Van den Berg LH, Veldink JH (2012). CGC-repeat expansion in FMR1 is not associated with amyotrophic lateral sclerosis. Neurobiology of Aging 33, 1852.
Koppers M, Van Bitterswijk M, Vlam L, Rowicka P, Van Vught PWJ, Groen EJN, Pasterkamp RJ, Veldink JH, Van den Berg LH (2012). VCP mutations in familial and sporadic amyotrophic lateral sclerosis in the Netherlands. Neurobiology of Aging 33, 837.
Diekstra FP, Van Vught PWJ, Van Rheenen W, Koppers M, Pasterkamp RJ, Van Es MA, Schelhaas HJ, De Visser M, Robberecht W, Andersen PM, Van den Berg LH, Veldink JH (2012). UNC13A is a modifier of survival in amyotrophic lateral sclerosis. Neurobiology of Aging 33, 630.
Zhou Y, Gunput RA, Adolfs Y, Fuller S, Li KW, Van der Schors RC, Smit AB, Sugden P, Hemming B, Hergovich A, Pasterkamp RJ (2011). MICAL-1 is a negative regulator of NDR-MST signaling and apoptosis. Molecular Cellular Biology, 31, 3603-3615.
Van Es MA, Schelhaas HJ, Van Vught PWJ, Andersen PM, Fumoto K, Groen EJN, Blauw HM, Koppers M, Schulte C, Diekstra FP, Bloem BR, Scheffer H, Van Nuenen BFL, Van Blitterswijk M, Van Rheenen W, Van Damme P, Lemmens R, Dahlberg C, Birve A, Fernández-Santiago R, Waibel S, Klein C, Weber M, Van der Kooi AJ, De Visser M, Verbaan D, Van Hilten JJ, Heutink P, Hennekam EAM, Cuppen E, De Bakker PIW, Berg D, Gasser T, Ludolph AC, Robberecht W, Ophoff RA, Veldink JH, Pasterkamp RJ, Van de Warrenburg BP, Van den Berg LH (2011). Rare mutations in ANG confer large risk for ALS and Parkinson’s disease. Ann Neurol 70, 964-973.
Caprini G, Zucchini D, Pasterkamp RJ, Tedischi G, Vanoni M (2011). Kinetic and spectroscopic characterization of the putative monooxygenase domain of human MICAL-1. Arch Biochem Biophys 515, 1-13.
Vorstman JA, van Daalen E, Jalali GR, Schmidt ER, Pasterkamp RJ, de Jonge M, Hennekam EA, Janson E, Staal WG, van der Zwaag B, Burbach JP, Kahn RS, Emanuel BS, van Engeland H, Ophoff RA (2011). A double hit implicates DIAPH3 as an autism risk gene. Mol Psychiatry 16, 442-451.
Messina A, Ferraris N, Cagnoni G, Wray S, Derijck AAH, Adolfs Y, Fasolo A, Pasterkamp RJ, Giacobini P (2011). Semaphorin7A guides migration of GnRH-1 neurons during development. Human Molecular Genetics 20, 4759-4774.
Zhou Y, Gunput RA, Adolfs Y, Pasterkamp RJ (2011). MICALs in control of the cytoskeleton, exocytosis and cell death. Cell Mol Life Sciences 68, 4033-4044.
Grigoriev I, Yu KL, Sanchez-Martinez E, Afonso Serra Marques A, Keijzer N, Demmers J, Peranen J, Pasterkamp RJ, Van der Sluijs P, Hoogenraad CC, Akhmanova A (2011). Rab6 and Rab8 cooperate in controlling docking and fusion of exocytotic carriers. Current Biology 21, 967-974.
Fenstermaker AG, Blokker AA, Bechara A, Adolfs Y, Tissir F, Goffinet A, Zou Y, Pasterkamp RJ (2010). Wnt-Planar Cell Polarity signaling controls the anterior-posterior organization of monoaminergic axons in the brainstem. J Neurosci 30, 16053-16064.
De Backer MWA, Brans MAD, Luijendijk MCM, Garner KM, Van den Heuvel DMA, Pasterkamp RJ, Adan RAH (2010). Neuropeptide delivery to the brain: a von Willebrand factor signal peptide to direct neuropeptide secretion. BMC Neuroscience 11, 94.
Derijck AAHA, Van Erp S, Pasterkamp RJ (2010). Semaphorin signaling: molecular switches at the midline. Trends Cell Biology 20, 568-576.
Groen EJ, van Es MA, van Vught PW, Spliet WG, van Engelen-Lee J, de Visser M, Wokke JH, Schelhaas HJ, Ophoff RA, Fumoto K, Pasterkamp RJ, Dooijes D, Cuppen E, Veldink JH, van den Berg LH (2010). FUS mutations in familial amyotrophic lateral sclerosis in the Netherlands. Arch Neurology 67, 224-230.
Kolk SM, Gunput RA, Tran TS, van den Heuvel DMA, Hellemons AJ, Adolfs Y, Ginty DD, Kolodkin AL, Burbach JPH, Smidt MP, Pasterkamp RJ (2009). Semaphorin3F is a bifunctional guidance cue for dopaminergic axons and regulates their fasciculation, channeling, rostral growth and intracortical targeting. J Neurosci 29, 12542-12557.
Van Es MA, Veldink JH, Saris CGJ, Blauw HM, van Vught PWJ, Birve A, Lemmens R, Schelhaas HJ, Groen EJN, Huisman MHB, van der Kooi AJ, de Visser M, Rivadeneira F, Hofman A, Rujescu D, Strengman E, Goldstein D, Muglia P, Slowik A, Uitterlinden AG, Waibel S, Meyer T, Ludolph AC, Glass JD, Purcell S, Landers J, Vermeulen SHM, Kiemeney LA, Wokke JHJ, Cronin S, Hardiman O, Fumoto K, Pasterkamp RJ, Meninger V, Melki J, Leigh PN, Shaw CE, Al-Chalabi A, Brown Jr. RH, Robberecht W, Andersen PM, Ophoff RA, van den Berg LH (2009). Genome-wide association study identifies UNC13A and 9p21.2 as susceptibility loci for sporadic Amyotrophic Lateral Sclerosis. Nat Genetics 41, 1083-1087.
Pasterkamp RJ, Giger RJ (2009). Semaphorin function in neural plasticity and disease. Curr Opinion Neurobiol 19, 263-274.
Degano AL, Pasterkamp RJ, Ronnett GV (2009). MeCP2 deficiency disrupts axonal guidance, fasciculation, and targeting by altering Semaphorin 3F function. Mol Cell Neurosci 42, 243-254.
Schmidt ERE, Pasterkamp RJ*, Van den Berg LH*(2009). Axon guidance proteins: novel therapeutic targets for ALS? Progress Neurobiol 88, 286-301. *Shared senior authors.
Van den Heuvel DMA, Pasterkamp RJ (2008). Getting connected in the dopamine system. Progress Neurobiol 85, 75-93.
Zhou Y, Gunput RA, Pasterkamp RJ (2008). Semaphorin signaling: progress made and future prospects. Trends Biochem Sciences 33, 161-170.
Suzuki K, Yamamoto M, Okuno T, Pasterkamp RJ, Takegahara N, Takamatsu H, Rennert PD, Kolodkin AL, Kumanogoh A, Kikutani H (2007). Semaphorin 7A initiates T cell-mediated inflammatory responses through alpha1/beta11 integrin. Nature 446, 680-684.
Pasterkamp RJ, Kolk SM, Hellemons AJCGM, Kolodkin AL (2007). Expression patterns of semaphorin7A and plexinC1 during rat neural development suggest roles in axon guidance and neuronal migration. BMC Dev Biol 7, 98.
Pasterkamp RJ, Verhaagen J (2006). Semaphorins in axon regeneration: developmental guidance molecules gone wrong? Royal Soc Phil Trans B 361, 1499-511.
Pasterkamp RJ, Dai HN, Terman JR, Wahlin KJ, Kim B, Bregman BS, Popovich PG, Kolodkin AL (2006). MICAL flavoprotein monooxygenases: expression during neural development and following spinal cord injuries in the at. Mol Cell Neurosci 31, 52-69.
Pasterkamp RJ (2005). R-Ras fills another GAP in Semaphorin signaling. Trends Cell Biol 15, 61-64.
Siebold S, Berrow N, Walter TS, Harlos K, Owens RJ, Stuart DI, Terman JR, Kolodkin AL, Pasterkamp RJ, Jones EY (2005). High-resolution structure of the catalytic region of MICAL, a multi-domain flavoenzyme signaling molecule. PNAS 102, 16836-16841.
Chabbert-de Ponnat I, Marie-Cardine A, Pasterkamp RJ, Schiavon V, Tamagnone L, Thomasset N, Bensussan A, Boumsell L (2005). Soluble CD100 functions on human monocytes and immature dendritic cells require plexin C1 and plexin B1, respectively. Int Immunol 17, 439-447.
Pasterkamp RJ, Kolodkin AL (2003). Semaphorin junction: making tracks toward neural connectivity. Curr Opin Neurobiol 13, 79-89.
Pasterkamp RJ, Peschon JJ, Spriggs MK, Kolodkin AL (2003). Semaphorin7A promotes axon outgrowth through integrins and MAPKs. Nature 424, 398-405 (article). Preview in Nature.
Terman JR, Mao T, Pasterkamp RJ, Yu H-H, Kolodkin AL (2002). MICALs, a family of conserved oxidoreductases, function in plexin-mediated axonal repulsion. Cell 109, 887-900.
De Winter F, Oudega M, Lankhorst AJ, Hamers FP, Blits B, Ruitenberg MJ, Pasterkamp RJ, Gispen WH, Verhaagen J (2002). Injury induced class 3 semaphorin expression in the rat spinal cord. Exp Neurol 175, 61-75.
Pasterkamp RJ, Verhaagen J (2001). Emerging roles for semaphorins in neural regeneration. Brain Res Rev 35, 36-54.
Pasterkamp RJ, Giger RJ, Baker RE, Hermens WTJMC, Verhaagen J (2000). Ectopic adenoviral vector-directed expression of Sema3A in organotypic spinal cord explants inhibits growth of primary sensory afferents. Dev Biol 220, 129-141.
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